The report by professional services firm KPMG looked at the finances of 39 clubs based on their popularity on social media channels, revenues for the 2014-15 and 2015-16 seasons, and success in European competitions.
Despite two relatively disappointing seasons on the pitch between 2014 and 2016, United’s value surged clear of Real Madrid and Barcelona last year, becoming the first club to break the three billion euros (£2.7 billion, $3.4 billion) mark for enterprise value.
Bayern Munich remain in fourth place, while Manchester City edge past Arsenal to take fifth spot, both with enterprise values of just under £1.7 billion.
Chelsea, Liverpool, Juventus and Spurs fill the next four positions, which means six of the 10 are from the Premier League.
In a statement, KPMG’s global head of sports Andrea Sartori said: “The aggregate value of Europe’s leading football clubs suggests that the overall value of football, as an industry, has grown.
“While this is partially explained by football’s broadcasting boom, the internationalisation of the clubs’ commercial operations, their investment into privately owned and modern facilities, and overall more sustainable management practices are also key reasons for this growth.
“In terms of media rights value, the English Premier League sits comfortably at the top of European leagues, although other major leagues have outlined well-defined strategies to compete for the attention of global fans.”